I just found this question on Quora. So, Goku’s battle with Beerus, the God of Destruction, was a pivotal moment in Dragon Ball Super. During their fight, Goku did use the Kamehameha, but it wasn’t his primary strategy. The reason for this is multifaceted.
Firstly, Beerus’s power level was far beyond anything Goku had faced before. Even in his Super Saiyan God form, Goku realized that conventional attacks like the Kamehameha might not be effective against someone of Beerus’s caliber. Beerus’s ability to effortlessly counter and deflect powerful attacks, including Goku’s Kamehameha, demonstrated the vast gap in their power levels.
Additionally, Goku’s approach to fighting Beerus was more about testing his limits and understanding the true extent of Beerus’s power. He knew that relying solely on familiar techniques wouldn’t be enough.
Instead, Goku focused on adapting and learning during the battle, trying to push his own boundaries and discover new ways to challenge Beerus. In essence, while Goku did use the Kamehameha during his fight with Beerus, it was clear that he needed to think beyond his usual techniques to stand a chance against such a formidable opponent.